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Mechanistically, impaired iron exporte.g., zinc-mediated inhibition of amyloid precursor protein (APP) ferroxidase activityprovides a route to local iron accumulation (Molinuevo et al., 2018)

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The researchers found that CJC-1295 was safe and relatively well tolerated when administered at doses of 30 or 60 g/kg, without any notable adverse effects observed

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